Description
Product Characteristics:
Aliases: Extracellular sulfatase Sulf 2 antibody, Extracellular sulfatase Sulf-2 antibody, HSulf-2 antibody, HSulf2 antibody, Sulf2 antibody, SULF2_HUMAN antibody
Target Information: Heparan sulfate proteoglycans (HSPGs) act as coreceptors for numerous heparin-binding growth factors and cytokines and are involved in cell signaling. Heparan sulfate 6-O-endosulfatases, such as SULF2, selectively remove 6-O-sulfate groups from heparan sulfate. This activity modulates the effects of heparan sulfate by altering binding sites for signaling molecules (Dai et al., 2005 [PubMed 16192265]).[supplied by OMIM, Mar 2008]